Department of Medical Affairs & Pharmacovigilance • Clinical Formulary Monograph
D 92/6 Okhla Phase 1, New Delhi, 110020, India • Medical Helpline: +91 11-47532297 • Email: contact@vrmedhealthcare.com
Glifoster
Sulfonylurea & Sustained-Release Biguanide Bilayer Tablet
Glifoster
Sulfonylurea & Sustained-Release Biguanide Bilayer Tablet
Glimepiride IP 2mg + Metformin Hydrochloride IP 500mg (Sustained Release)
Product Clinical Overview
Glifoster is an uncoated bilayered tablet combining Glimepiride, a third-generation sulfonylurea, with sustained-release Metformin Hydrochloride. The bilayer design delivers immediate glimepiride action alongside extended metformin release for glycaemic control in type 2 diabetes mellitus.
More Images
Actual Glifoster packaging, label panels and blister strip.
Key Ingredients & Pharmacological Profiles
Active chemical constituents, standardized strengths, and physiological roles.
Sulfonylurea stimulating pancreatic beta-cell insulin secretion.
Sustained-release biguanide reducing hepatic glucose output.
Approved Clinical Indications
Clinical contexts where this formulation is prescribed under medical supervision.
Pharmacological Mechanism of Action
Glimepiride binds the sulfonylurea receptor on beta-cell K-ATP channels, triggering insulin release. Metformin lowers hepatic gluconeogenesis and improves insulin sensitivity; the SR matrix extends its absorption window.
Formulation & Delivery Technology
- Bilayer technology separates immediate and sustained-release layers
- SR metformin improves gastrointestinal tolerability
- Supports once-daily dosing with the morning meal
VR Med Healthcare Pvt. Ltd.
Registered Office & Facility:D 92/6 Okhla Phase 1, New Delhi, 110020, India
Quality Certifications:WHO-GMP Compliant & ISO 9001:2015 Certified
Medical Helpline:+91 11-47532297
Corporate Email:contact@vrmedhealthcare.com
Administration & Packaging Details
As directed by the Physician. Tablet should be swallowed whole and not chewed or crushed.
10 x 10 Tablets (Blister Strip)
Store in a cool, dry and dark place. Protect from light and moisture.
This formulation monograph is published strictly for the professional scientific reference and educational use of Registered Medical Practitioners, Hospitals, and Clinical Laboratories. The technical and pharmacological details presented herein do not constitute medical advice, diagnostic opinion, or therapeutic claims. These products must be prescribed, dispensed, and administered strictly in accordance with local drug regulations and under the supervision of a licensed physician. VR Med Healthcare Pvt. Ltd. does not promote self-medication, off-label usage, or unsolicited consumer health claims.
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Enhancing Lives With
Quality Healthcare & Integrity.
VR Med Healthcare has been a trusted benchmark in the Indian pharmaceutical sector since 2010. Headquartered in Okhla Phase 1, New Delhi, our dedicated team of over 100 professionals collaborates with leading physicians and distributors across India to make premium medicines accessible and reliable.
“Our goal is to deliver quality of care in a courteous, respectful, and compassionate manner. We hope you will allow us to care for you and strive to be the first and best choice for healthcare professionals and families.”
Kamal Choudhary
Managing Director, VR Med Healthcare
Established
Approved Formulations
Healthcare Specialists
Manufacturing Standard